Comments from Website author: Article discusses how redox, the opposite reaction to that affected by an antioxidant (anti-ox-idant), is causative in the inflammation reaction of rheumatoid arthritis. They state this to be a result of an antioxidant depletion.
Comments from Physicians at this article's end: None

The joint, a redox sensitive microenvironment?--an hypothesis.

Scand J Rheumatol Suppl Vol. 101 pp. 131-6

Medline®

DATE: 1995

Abstract

Antioxidant depletion in a normal adult increases the risk of developing rheumatoid arthritis (1). We discuss how redox processes "control" the inflammatory reaction and suggest that the synovium is a peculiarly "redox-sensitive" microenvironment. This discussion will be illustrated by a zonal model of tissue injury to represent the diseased synovium.

Sahinoglu T Stevens CR Blake DR

Number of references: 20

Language: Eng

Primary Author's Address: London Hospital Medical College, U.K.

Country: SWEDEN

MeSH Headings: Animal Arthritis/physiopathology Human Joints/*metabolism/physiopathology Models, Biological/* Oxidation-Reduction Support, Non-U.S. Gov't Synovial Membrane/*metabolism/physiopathology

Medlars UID 95265926