Comments from Website
author: In the type of use described below, remember that silver
(as a salt here, not a colloid) has a short-term application, not
a continued ingestion of many
months.
Comments from Physicians at
this article's end: None
Silver sulfadiazine: an antibacterial
agent for topical use in burns. A review of the literature.
Scand J Plast Reconstr Surg 18: 119-26
(1984)[84250044]
Abstract:
Topical antibacterial treatment is of major importance in
the burn patient. Silver
sulfadiazine is an effective agent with low toxicity and few
side effects. Deposition of silver in
tissues, and absorption of sulfadiazine are both minimal.
Present and future problems are represented by the emergence
of resistant Gram negative bacilli, including Pseudomonas
aeruginosa. The development of related metal sulfadiazines to
be used against resistant
bacteria is on an investigational stage, and
clinical trials are few. Silver sulfadiazine may be used in a
variety of other conditions than burns.
S. Hoffmann