Comments from Website author: Let us not forget that
any discoloration of this type can be as devastating emotionally as any illness could ever
be.
Comments from Physicians at this article's end: None
Systemic argyria secondary to topical silver
nitrate.
Arch Dermatol, 113: 8, 1977 Aug, 1077-9
-
- Abstract
- A case of generalized argyria secondary to topical silver nitrate
use on the oral mucosa is described, and the nature and history of argyria reviewed. The
patient has extreme pigmentation of her skin and abdominal viscera, as seen on physical
examination, gastroduodenoscopy, and laparotomy. Her use of silver nitrate applicators was
uncontrolled by her dentist and pharmacist, and the diagnosis
of argyria was not made until 2 1/2 years of heavy usage had passed. Avoidance of similar cases requires the careful scrutiny of
silver-containing medicinal usage by all health practitioners and pharmacists. Although
the systemic distribution of silver in both elemental and ionic forms can be linked with
no systemic toxicity, the resultant pigmentation can
be devastating to the patient.
-
- Marshall JP 2d; Schneider RP
-
- Language of Publication
- English
- Unique Identifier
- 77240886

- MeSH Heading (Major)
- Argyria [*ET/PA], Silver Nitrate [*AE/TU]
- MeSH Heading
- Case Report, Female, Gastrointestinal System [PA],
Gingival Hemorrhage [DT], Human, Middle Age, Skin [PA]

- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0003-987X
- Country of Publication
- UNITED STATES