Comments from Website author: Let us not forget that any discoloration of this type can be as devastating emotionally as any illness could ever be.
Comments from Physicians at this article's end: None

 

Systemic argyria secondary to topical silver nitrate.

Arch Dermatol, 113: 8, 1977 Aug, 1077-9

 
Abstract
A case of generalized argyria secondary to topical silver nitrate use on the oral mucosa is described, and the nature and history of argyria reviewed. The patient has extreme pigmentation of her skin and abdominal viscera, as seen on physical examination, gastroduodenoscopy, and laparotomy. Her use of silver nitrate applicators was uncontrolled by her dentist and pharmacist, and the diagnosis of argyria was not made until 2 1/2 years of heavy usage had passed. Avoidance of similar cases requires the careful scrutiny of silver-containing medicinal usage by all health practitioners and pharmacists. Although the systemic distribution of silver in both elemental and ionic forms can be linked with no systemic toxicity, the resultant pigmentation can be devastating to the patient.
 
Marshall JP 2d; Schneider RP
 
Language of Publication
English
Unique Identifier
77240886

MeSH Heading (Major)
Argyria [*ET/PA], Silver Nitrate [*AE/TU]
MeSH Heading
Case Report, Female, Gastrointestinal System [PA], Gingival Hemorrhage [DT], Human, Middle Age, Skin [PA]

Publication Type
JOURNAL ARTICLE
ISSN
0003-987X
Country of Publication
UNITED STATES