Comments from Website author: Silver seems to have
an effect on central nervous system function.
Comments from Physicians at this article's end: None
Hypoactivity in silver exposed mice.
Acta Pharmacol Toxicol (Copenh), 55: 5, 1984 Nov, 398-401
- Abstract
- The functional implications of the presence of silver in the central nervous system are
unknown. Since silver is present in the environment and
since systemic silver poisoning leads to intraneuronal accumulations of the metal we have
evaluated the possible effects of silver on the open field behaviour of mice.
Argyric mice have been compared with controls in three experiments, one including long
term administration of 0.015% silver nitrate in the drinking water and two in which the
reactions of male and female mice to shock doses of silver lactate have been studied. In all experiments the silver treated mice were hypoactive. We
suggest that this hypoactivity is due to an influence of silver upon the functional status
of the CNS.
-
- Rungby J; Danscher G
-
- Language of Publication
- English
- Unique Identifier
- 85145086
- MeSH Heading (Major)
- Argyria [ME/*PP], Motor Activity [*DE]
- MeSH Heading
- Animal, Brain [ME], Female, Male, Mice, Silver [ME]
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0001-6683
- Country of Publication
- DENMARK
- CAS Registry/EC Number
- 7440-22-4 (Silver)